| Nickel-Catalyzed Intramolecular Dual Annulation Reaction of Alkyl Nitrile-Containing 1,2,3-Benzotriazin-4(3H)-ones: A Pathway to Access Diversely Polycyclic Quinazolinone Alkaloids | |
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| 學年 | 111 |
| 學期 | 2 |
| 出版(發表)日期 | 2023-03-21 |
| 作品名稱 | Nickel-Catalyzed Intramolecular Dual Annulation Reaction of Alkyl Nitrile-Containing 1,2,3-Benzotriazin-4(3H)-ones: A Pathway to Access Diversely Polycyclic Quinazolinone Alkaloids |
| 作品名稱(其他語言) | |
| 著者 | Vijaykumar H. Thorat; Yong-Ran Huang; Hao-Yu Chao; Jen-Chieh Hsieh |
| 單位 | |
| 出版者 | |
| 著錄名稱、卷期、頁數 | Adv. Synth. Catal 366(9), p.2130−2135. |
| 摘要 | Herein, we report a nickel-catalyzed intramolecular dual annulation reaction of alkyl nitrile-containing 1,2,3-benzotriazin-4(3H)-ones to synthesize polycyclic quinazolinones. This catalytic reaction can construct the core structure of polycyclic quinazolinone alkaloids; therefore, we also apply this reaction as the critical step to access fifteen relevant alkaloids to demonstrate efficacy. |
| 關鍵字 | Nickel Catalysis; Denitrogenative Reaction; Addition of Nitrile; Intramolecular Cyclization; Polycyclic Quinazolinone |
| 語言 | en |
| ISSN | 1615-4169; 1615-4150 |
| 期刊性質 | 國外 |
| 收錄於 | SCI |
| 產學合作 | |
| 通訊作者 | |
| 審稿制度 | 否 |
| 國別 | DEU |
| 公開徵稿 | |
| 出版型式 | ,電子版,紙本 |
| 相關連結 |
機構典藏連結 ( http://tkuir.lib.tku.edu.tw:8080/dspace/handle/987654321/127671 ) |