Two-Dimensional Theoretical Analysis and Experimental Study of Mass Transfer in a Hollow-Fiber Dialysis Module Coupled with Ultrafiltration Operations
學年 111
學期 2
出版（發表）日期 2023-07-27
作品名稱 Two-Dimensional Theoretical Analysis and Experimental Study of Mass Transfer in a Hollow-Fiber Dialysis Module Coupled with Ultrafiltration Operations
作品名稱（其他語言）
著者 Ho, Chii-dong; Tu, Jr-wei; Chen, Yih-hang
單位
出版者
著錄名稱、卷期、頁數 Membranes 13(8),　702
摘要 This research theoretically and experimentally develops a hollow-fiber dialysis module coupled with ultrafiltration operations by introducing a trans-membrane pressure during the membrane dialysis process, which can be applied to the waste metabolic end products in the human body for improving the dialysis efficiency. The solutes were transported by both diffusion and convection from the concentration driving-force gradient between retentate and dialysate phases across the membrane, compared to the traditional dialysis processes by diffusion only. A two-dimensional modeling of such a dialysis-and-ultrafiltration system in the hollow-fiber dialysis module was formulated and solved using the stream function coupled with the perturbation method to obtain the velocity distributions of retentate and dialysate phases, respectively. The purpose of the present work is to investigate the effect of ultrafiltration on the dialysis rate in the hollow-fiber dialyzer with ultrafiltration operations. A highest level of dialysis rate improvement up to about seven times (say 674.65% under 𝑉𝑎=20 mL/min) was found in the module with ultrafiltration rate 𝑉𝑤=10 mL/min and membrane sieving coefficient 𝜃=1 , compared to that in the system without operating ultrafiltration. Considerable dialysis rate improvements on mass transfer were obtained by implementing a hollow-fiber dialysis-and-ultrafiltration system, instead of using the hollow-fiber dialyzer without ultrafiltration operation. The experimental runs were carried out under the same operating conditions for the hollow-fiber dialyzers of the two experimental runs with and without ultrafiltration operations for comparisons. A very reasonable prediction by the proposed mathematical model was observed.
關鍵字 hollow-fiber module;dialysis;ultrafiltration;device performance;dialysis-and-ultrafiltration system
語言 en
ISSN 2077-0375
期刊性質 國外
收錄於 SCI
產學合作
通訊作者 Chii-Dong Ho
審稿制度 是
國別 CHE
公開徵稿
出版型式 ,電子版