Attomolar analyte sensing technique for detection of Pb2+ and Hg2+ ions based on liquid crystal
學年 111
學期 2
出版（發表）日期 2023-02-01
作品名稱 Attomolar analyte sensing technique for detection of Pb2+ and Hg2+ ions based on liquid crystal
作品名稱（其他語言）
著者 Asma Verdian; Zahra Khoshbin; Chih-Hsin Chen; Qiongzheng Hu
單位
出版者
著錄名稱、卷期、頁數 Talanta 253, 124042
摘要 Detecting the ultra-low abundance of heavy metals in real samples remains challenging and it requires the development of high-performance biosensing modalities. This work describes a novel strategy for design an ultra-sensitive liquid crystal (LC) aptasensor, in which the LCs reorientation induced by conformational changes of a triple helix molecular switch (THMS) structure is utilized for the quantitative detection of Pb2+ and Hg2+ ions. The developed aptasensor exhibits a wide linear range with the ultralow detection limits as low as 0.021 aM and 0.068 aM for Pb2+ and Hg2+, respectively. Besides, the results show that other analytes cause no interference. Noteworthy, this sensing strategy is easy to expand for other targets by altering the aptamer sequence without change of the triple-helix structure and can be used for multiple analyte detection. The developed aptasensor is promising powerful platform as a LC AttoSens for precision screening of hazardous residues in food analysis.
關鍵字
語言 en
ISSN 1873-3573; 0039-9140
期刊性質 國外
收錄於 SCI
產學合作
通訊作者
審稿制度 否
國別 NLD
公開徵稿
出版型式 ,電子版
相關連結

機構典藏連結 ( http://tkuir.lib.tku.edu.tw:8080/dspace/handle/987654321/125613 )