Three-dimensional ultrasound in margin evaluation for breast tumor excision using mammotome
學年 92
學期 2
出版(發表)日期 2004-02-01
作品名稱 Three-dimensional ultrasound in margin evaluation for breast tumor excision using mammotome
著者 Dar-Ren Chen; Ruey-Feng Chang; Chii-Jen Chen; Chih-Chia Chang; Long-Bin Jeng
著錄名稱、卷期、頁數 Ultrasound in Medicine and Biology 30(2), p.169-179
摘要 Sonographic evidence of tumor removal by Mammotome® excision does not confirm histological clearance. The operator finds it hard to determine if a malignant tumor has been fully removed, leaving a safe margin in the direction of each border; that is, the spatial orientation during tumor retrieval is not well-established by naked eye under sonographic guidance. We propose a computational imaging process to extract reasonable tumor contour in pre- and postoperative data sets for sonographic guidance so that Mammotome® excision can help the operator to evaluate the surgical outcome. There were five tumors in the study, including three benign and two malignant. The lesion of interest was delineated after 2-D examination was completed, then it was analyzed with 3-D breast ultrasound (US). To give a reference point for correlations between pre- and postoperative images, we used a marker tape pasted on the skin within the transducer scanning area and then the preoperative 3-D US images were obtained. Subsequently, 2-D breast US was applied during Mammotome® operation. After the Mammotome® procedures were finished, the postoperative 3-D US images were obtained; thus, we gained two different data sets of 3-D US images that were used for later analysis for evaluating the extension of postoperative margin status. From the results, the safe margin was not satisfactory in all directions, because the minimum differences measured by the proposed algorithm were not large enough in all five cases, and this was proved from two malignant mastectomy specimens. The experimental results representing this inadequate Mammotome® excision can be visualized through the computer aid. The comparison of tumor contour and excision margin may possibly be used for small malignant tumors in the future to improve the breast-conserving surgery. (E-mail:
關鍵字 Mammotome®;Three-dimensional breast ultrasound;Computer
語言 en_US
ISSN 1879-291X;0301-5629
期刊性質 國外
收錄於 SCI
國別 USA
出版型式 ,電子版,紙本