教師資料查詢 | 類別: 期刊論文 | 教師: 謝仁傑HSIEH, JEN-CHIEH (瀏覽個人網頁)

標題:Synthesis of N-Heterocycles via Transition-Metal-Catalyzed Tandem Addition/ Cyclization of a Nitrile
學年108
學期1
出版(發表)日期2020/01/09
作品名稱Synthesis of N-Heterocycles via Transition-Metal-Catalyzed Tandem Addition/ Cyclization of a Nitrile
作品名稱(其他語言)
著者Jen-Chieh Hsieh(謝仁傑); Haw-Lih Su
單位
出版者
著錄名稱、卷期、頁數Synthesis 52(6), p.819–833
摘要The diverse methodologies to synthesize N-heterocycles through transition-metal-catalyzed cascade addition/cyclization of a nitrile are discussed in this review. Aspects relating to three types of transition-metal-catalyzed addition of a nitrile with subsequent cyclization include (1) a transition-metal acting as a Lewis acid to accelerate the nucleophilic addition of a nitrile, (2) the late-transition-metal-catalyzed 1,2-insertion of a nitrile, and (3) an in situ generated radical by transition-metal catalysis to implement a radical addition/cyclization tandem reaction. Applications for the synthesis of natural alkaloids, their derivatives, and some bioactive compounds are also summarized herein.
關鍵字transition-metal-catalyzed;nitrile addition;cyclization;N-heterocycles;natural alkaloids
語言英文
ISSN1437-210X
期刊性質國外
收錄於SCI;
產學合作
通訊作者
審稿制度
國別德國
公開徵稿
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