Transition-Metal-Free Tandem Cyclization/N-Arylation Reaction: A Method to Access Biaryl Sultam Derivatives via a Diradical Pathway
學年 109
學期 1
出版(發表)日期 2020-08-12
作品名稱 Transition-Metal-Free Tandem Cyclization/N-Arylation Reaction: A Method to Access Biaryl Sultam Derivatives via a Diradical Pathway
作品名稱(其他語言)
著者 Vijaykumar H. Thorat; Jen-Chieh Hsieh (謝仁傑); Chien-Hong Cheng
單位
出版者
著錄名稱、卷期、頁數 Organic Letter 22(16), p.6623–6627
摘要 A novel procedure for the transition-metal-free tandem cyclization/N-arylation reaction sequence of an aryne with a 1,2,3,4-benzothiatriazine-1,1-dioxide is reported. This reaction goes through the intramolecular homolytic cyclization to generate an N–H biaryl sultam intermediate, which enables aryne insertion to access diversely functionalized biaryl sultam derivatives with high yields. The mechanism study indicates that homolytic cyclization is executed by a diradical species, initiated from the thermal decomposition of 1,2,3,4-benzothiatriazine-1,1-dioxide to release a nitrogen molecule.
關鍵字
語言 en
ISSN 1523-7052
期刊性質 國外
收錄於 SCI
產學合作
通訊作者
審稿制度
國別 USA
公開徵稿
出版型式 ,電子版
相關連結

機構典藏連結 ( http://tkuir.lib.tku.edu.tw:8080/dspace/handle/987654321/120972 )