A SERS method with attomolar sensitivity: a case study with the flavonoid catechin
學年 106
學期 1
出版(發表)日期 2018-01-17
作品名稱 A SERS method with attomolar sensitivity: a case study with the flavonoid catechin
作品名稱(其他語言)
著者 Chia-Chi Huang; Wenlung Chen
單位
出版者
著錄名稱、卷期、頁數 Microchimica Acta 185, 120
摘要 Making good use of interactions between analyte molecules and the metal nanoparticles is key to impact the detection limit in a surface-enhanced Raman scattering (SERS) based detections. SERS was applied to the analysis of catechin and it was found that the relative abundance of catechin in the sample to citrate-capped AgNPs and the aggregation agent NaCl plays a critical role in the quality of detection. At a component volume ratio of 6:2:1 (catechin:AgNPs:NaCl), catechin can be detected at µM levels. When the ratio is 12:2:1, Raman signals are discernible even at the attomolar concentration level (10−18 M). Under these conditions, the SERS mechanisms and the force of laser tweezers function best. The extent of signal enhancement enabled an ultrasensitive and reproducible Raman spectroscopic determination of catechin.
關鍵字 Raman spectroscopy;Citrate-capped AgNPs;Aggregation agent;Attomolar detection
語言 en_US
ISSN 1436-5073
期刊性質 國外
收錄於 SCI
產學合作
通訊作者
審稿制度
國別 AUT
公開徵稿
出版型式 ,電子版,紙本
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