|標題：Paper-Based Flexible Surface Enhanced Raman Scattering Platforms and Their Applications to Food Safety|
|作品名稱||Paper-Based Flexible Surface Enhanced Raman Scattering Platforms and Their Applications to Food Safety|
|著者||Chia-Chi Huang; Chi-Yun Cheng; Yen-Shi Lai|
|著錄名稱、卷期、頁數||Trends in Food Science & Technology 100, P.349-358|
Surface enhanced Raman scattering (SERS) based on highly sensitive, flexible, solid-state sensors can provide molecular vibrational fingerprints of targeted substances in point-of-care (POC) analysis. Cellulose paper offers many advantages for the build-up of silver and gold nanostructures on a three-dimensional scaffold. Such composites can be made to contain SERS hot spots required for sensitive SERS detection in an active solid-state sensor.
Scope and approach
In this review, we discuss the key technical issues involved in the fabrication of SERS sensors combining a metallic SERS substrate and a cellulose paper support. We then survey recent literature for methods designed to address these issues with applications to support food safety where POC analysis serves as a valuable tool.
Key findings and conclusions
Sensitivity of detection is a primal challenge in the development of a paper-based SERS substrate. The fibril structures of paper materials, a suitable modification for improved bonding at the paper-metal interface, and the surface conditions of metal nanostructures all contribute to sensitive SERS performance on paper. Continuing expansion of spectrum collection in a database format, diverse methods for the statistical analyses of Raman spectra, and advanced integration of portable Raman instruments with the mobile tele-networks are critical in the further development of flexible SERS sensor in POC testing of food-borne substances.
|關鍵字||Surface enhanced Raman scattering spectroscopy (SERS);Flexible SERS sensors;Point-of-care (POC);Cellulose paper platform;Food safety|