UV-protective activities of pineapple leaf extract in zebrafish embryos.
學年 107
學期 1
出版（發表）日期 2019-01-01
作品名稱 UV-protective activities of pineapple leaf extract in zebrafish embryos.
作品名稱（其他語言）
著者 Yau-Hung Chen; Yue-Jyun Chen; Chi-Yuan Chou; Chi-Chung Wen; Chien-Chung Cheng
單位
出版者
著錄名稱、卷期、頁數 Research on Chemical Intermediates 45(1), p.65-75
摘要 The UV-protective activities of pineapple leaf extract in a zebrafish model have been evaluated by recording fin morphological changes. UV protective effects of pineapple leaf extract was evaluated using Kaplan–Meier analysis and Cox proportional hazards regression. The results showed that (1) the mean time of return to normal fin in the UV + pineapple leaf extract (100 and 400 μg/mL) groups are 3.90 and 2.50 days, respectively, more quickly than in the UV only group (4.12 days); (2) zebrafish fins in the pineapple leaf extract (100 and 400 μg/mL) groups are 1.44 and 4.29 times, respectively, more likely to return to recover than those in the UV only group; and (3) pineapple leaf extract has UV-absorbance abilities and significantly reduces p53 expressions and ROS generation in UV-exposed zebrafish embryos, which may attenuate UV-mediated apoptosis.
關鍵字 Embryo;Fin;Pineapple;UV;Zebrafish
語言 en_US
ISSN 0922-6168
期刊性質 國外
收錄於 SCI SSCI
產學合作
通訊作者
審稿制度 否
國別 USA
公開徵稿
出版型式 ,電子版
相關連結

機構典藏連結 ( http://tkuir.lib.tku.edu.tw:8080/dspace/handle/987654321/117040 )