| Synthesis of Novel Isoquinolino[5,4-ab]phenanthridine Derivatives via Pictet–Spengler Reaction | |
|---|---|
| 學年 | 107 |
| 學期 | 2 |
| 出版（發表）日期 | 2019-03-03 |
| 作品名稱 | Synthesis of Novel Isoquinolino[5,4-ab]phenanthridine Derivatives via Pictet–Spengler Reaction |
| 作品名稱（其他語言） | |
| 著者 | Tsai, Min-Chen; Huang, Pei Yu; Syu, Liang Sheng; Shih, Tzenge-Lien |
| 單位 | |
| 出版者 | |
| 著錄名稱、卷期、頁數 | Synthesis 51(6), pp.1377-1382 |
| 摘要 | The reaction of 5-amino-2-[2 (dimethylamino)ethyl]-6-phenyl-1H-benzo[de]isoquinoline-1,3(2H)-dione with a series of aldehydes in acidic media (phosphoric acid, trifluoromethanesulfonic acid, and trifluoroacetic acid) is described. This key step is based on the Pictet–Spengler reaction to synthesize ten novel isoquinolino[5,4-ab]phenanthridine derivatives. The most effective acid is phosphoric acid and optimized yields were obtained. The frameworks of target compounds are unique and have never been reported. |
| 關鍵字 | homophthalimide;isoquinoline-1,3-dione;naphthalimide ;phenanthridine;Pictet;Spengler reaction;Suzuki–Miyaura cross-coupling reaction |
| 語言 | en |
| ISSN | 1377-1382 |
| 期刊性質 | 國外 |
| 收錄於 | SCI |
| 產學合作 | |
| 通訊作者 | |
| 審稿制度 | 否 |
| 國別 | DEU |
| 公開徵稿 | |
| 出版型式 | ,電子版 |
| 相關連結 |
機構典藏連結 ( http://tkuir.lib.tku.edu.tw:8080/dspace/handle/987654321/115975 ) |
| SDGS | 良好健康和福祉,優質教育 |
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