A reevaluation and discussion on the threshold limit for hemolysis in a turbulent shear flow
學年 90
學期 1
出版（發表）日期 2001-10-01
作品名稱 A reevaluation and discussion on the threshold limit for hemolysis in a turbulent shear flow
作品名稱（其他語言）
著者 盧博堅; Lu, Po-chien; Lai, Ho-cheng; 劉佳興; Liu, Jia-Shing
單位 淡江大學水資源及環境工程學系
出版者 Elsevier
著錄名稱、卷期、頁數 Journal of biomechanics 34(10), pp.1361-1364
摘要 One major factor of red blood cell damage induced by artificial heart valves is the magnitude of turbulent shear stresses in the flow field. An often-cited threshold for hemolysis is 400 N/m2 (Sallam and Hwang, Biorheology 21 (1984) 783). This value, however, was measured with a one-component laser Doppler anemometer and was not calculated from the major principal Reynolds shear stress, therefore underestimatng the threshold. This study performed flow field measurements under similar conditions, using a two-component laser Doppler anemometer and determining major principal Reynolds shear stress, to reevaluate the hemolytic threshold as 800 N/m2 with an exposure time of 1 ms. The Kolmogorov length scales, approximately 9 μm, are capable of inflicting direct damage to the red blood cells. These results will serve as a more accurate reference in future heart valve design and testing.
關鍵字
語言 en
ISSN 0021-9290
期刊性質 國外
收錄於
產學合作
通訊作者
審稿制度 否
國別 TWN
公開徵稿
出版型式 ,電子版
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