標題:A reevaluation and discussion on the threshold limit for hemolysis in a turbulent shear flow |
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學年 | 90 |
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學期 | 1 |
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出版(發表)日期 | 2001/10/01 |
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作品名稱 | A reevaluation and discussion on the threshold limit for hemolysis in a turbulent shear flow |
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作品名稱(其他語言) | |
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著者 | 盧博堅; Lu, Po-chien; Lai, Ho-cheng; 劉佳興; Liu, Jia-Shing |
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單位 | 淡江大學水資源及環境工程學系 |
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出版者 | Elsevier |
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著錄名稱、卷期、頁數 | Journal of biomechanics 34(10), pp.1361-1364 |
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摘要 | One major factor of red blood cell damage induced by artificial heart valves is the magnitude of turbulent shear stresses in the flow field. An often-cited threshold for hemolysis is 400 N/m2 (Sallam and Hwang, Biorheology 21 (1984) 783). This value, however, was measured with a one-component laser Doppler anemometer and was not calculated from the major principal Reynolds shear stress, therefore underestimatng the threshold. This study performed flow field measurements under similar conditions, using a two-component laser Doppler anemometer and determining major principal Reynolds shear stress, to reevaluate the hemolytic threshold as 800 N/m2 with an exposure time of 1 ms. The Kolmogorov length scales, approximately 9 μm, are capable of inflicting direct damage to the red blood cells. These results will serve as a more accurate reference in future heart valve design and testing. |
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關鍵字 | |
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語言 | 英文 |
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ISSN | 0021-9290 |
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期刊性質 | 國外 |
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收錄於 | |
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產學合作 | |
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通訊作者 | |
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審稿制度 | 否 |
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國別 | 中華民國 |
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公開徵稿 | |
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出版型式 | ,電子版 |
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