Modeling the release of a reagent from an inwardly tapered disk with a central hole
學年 104
學期 2
出版（發表）日期 2016-06-01
作品名稱 Modeling the release of a reagent from an inwardly tapered disk with a central hole
作品名稱（其他語言）
著者 Shiojenn Tseng, Ron-Ren Su, Jyh-Ping Hsu, Chur-Jen Chen
單位
出版者
著錄名稱、卷期、頁數 Journal of Engineering Mathematics 98(1), p.1-9
摘要 A theoretical analysis on the controlled release of an active reagent from an inwardly tapered polymeric disk with a central releasing hole proposed originally by Bechard and McMullen (J Pharm Sci 77:222–228, 1988) is conducted. Analytic expressions for the temporal variations in the amount of reagent released and the size of the unreleased portion of the device are derived. Relaxing their assumptions of pseudo-steady and constant reagent concentration in the hole, the problem is reanalyzed. The resultant model is suitable to the whole release period, and successfully describes their experimental data. To make the analytic result derived more readily applicable, the results for some special cases are also presented.
關鍵字 Controlled-release; Inwardly tapered disk; Unsteady-state model
語言 en
ISSN
期刊性質 國外
收錄於 SCI EI
產學合作
通訊作者
審稿制度 否
國別 NLD
公開徵稿
出版型式 ,電子版,紙本
相關連結

機構典藏連結 ( http://tkuir.lib.tku.edu.tw:8080/dspace/handle/987654321/111767 )