Nickel Catalyzed Highly Chemo- and Stereoselectively Borylative Cyclization of 1,6-Enynes with Bis(pinacolato)diboron | |
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學年 | 105 |
學期 | 2 |
出版(發表)日期 | 2017-05-17 |
作品名稱 | Nickel Catalyzed Highly Chemo- and Stereoselectively Borylative Cyclization of 1,6-Enynes with Bis(pinacolato)diboron |
作品名稱(其他語言) | |
著者 | Jen-Chieh Hsieh; Ya-Chun Hong; Chun-Ming Yang; Subramaniyan Mannathanb; Chien-Hong Cheng |
單位 | |
出版者 | |
著錄名稱、卷期、頁數 | Organic Chemistry Frontiers 4, p.1615–1619 |
摘要 | A highly chemo- and stereoselective nickel-catalyzed borylative cyclization of 1,6-enynes with bis(pinacolato)diboron is described. Enynes containing an electron-deficient alkene such as a vinyl ketone provided alkenylboronates while enynes containing a terminal alkene gave homoallylic boronates. A plausible mechanism involving a nickelacyclopentene intermediate is proposed. In addition, the resulted alkenyl- or homoallylic boronates can be transformed to the corresponding ketones and alcohols via oxidation. Application to a palladium-catalyzed cross coupling reaction of alkenylboronates with aromatic halides has been demonstrated as well. |
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語言 | en |
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期刊性質 | 國外 |
收錄於 | SCI |
產學合作 | |
通訊作者 | |
審稿制度 | 是 |
國別 | GBR |
公開徵稿 | |
出版型式 | ,電子版,紙本 |
相關連結 |
機構典藏連結 ( http://tkuir.lib.tku.edu.tw:8080/dspace/handle/987654321/113426 ) |