Preparation and properties of PCL hollow fiber and its guidance on the proliferation of Schwann cells
學年 104
學期 2
發表日期 2016-07-25
作品名稱 Preparation and properties of PCL hollow fiber and its guidance on the proliferation of Schwann cells
作品名稱（其他語言）
著者 Lien, Wei; Cheng, Liao-Ping; Lee, Chia-Fen; Don, Trong-Ming
作品所屬單位
出版者
會議名稱 The 32th International Conference of the Polymer Processing Society (PPS-32)
會議地點 Lyon, France
摘要 Asymmetric polycaprolactone (PCL) hollow fiber was prepared by wet spinning method for the guidance on the proliferation of Schwann cells. The PCL was dissolved in DMAc as solvent incorporated with tween20 as a pore former to modify the structure and the isopropanol solution was used as a soft coagulant. The dope solution with 18wt.% tween20 and 18wt.% PCL was extruded simultaneously with 15% (v/v) isopropanol solution as bore solution from the annulus-shape nozzle. After passing through 10-cm residence air gap, the fiber was immersed in the 25% (v/v) isopropanol solution bath where coagulation occurred. Scanning electron microscope was used to observe the morphologies of the prepared hollow fibers. The results indicated that the hollow fiber inner surface had pore sizes ranging from 10 to 15 micron. On the other hand, the outer surface was smooth and dense. Furthermore, tensile mechanical properties and thermal properties of the PCL hollow fiber were measured. The culture of Schwann cells inside the hollow fiber was also evaluated.
關鍵字
語言 en
收錄於
會議性質 國際
校內研討會地點 無
研討會時間 20160725~20160729
通訊作者
國別 FRA
公開徵稿
出版型式
出處 The 32th International Conference of the Polymer Processing Society Proceeding
相關連結

機構典藏連結 ( http://tkuir.lib.tku.edu.tw:8080/dspace/handle/987654321/107550 )