Hydride-Induced Anionic Cyclization: An Efficient Method for the Synthesis of 6-H-Phenanthridines via a Transition-Metal-Free Process | |
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學年 | 103 |
學期 | 2 |
出版(發表)日期 | 2015-03-12 |
作品名稱 | Hydride-Induced Anionic Cyclization: An Efficient Method for the Synthesis of 6-H-Phenanthridines via a Transition-Metal-Free Process |
作品名稱(其他語言) | |
著者 | 謝仁傑 |
單位 | |
出版者 | ACS |
著錄名稱、卷期、頁數 | Organic Letters 17(6), p.1613-1616 |
摘要 | A novel procedure for hydride-induced anionic cyclization has been developed. It includes the reduction of a biaryl bromo-nitrile with a nucleophilic aromatic substitution (SNAr). A range of polysubstituted 6-H-phenanthridines were so obtained in moderate to good yield with good substrate tolerance. This method involves a concise transition-metal-free process and was applied to synthesize natural alkaloids. |
關鍵字 | |
語言 | en_US |
ISSN | 1523-7060 |
期刊性質 | 國外 |
收錄於 | SCI |
產學合作 | |
通訊作者 | 謝仁傑 |
審稿制度 | 否 |
國別 | USA |
公開徵稿 | |
出版型式 | ,電子版 |
相關連結 |
機構典藏連結 ( http://tkuir.lib.tku.edu.tw:8080/dspace/handle/987654321/103479 ) |