Cluster-based Classification of Diabetic Nephropathy among Type 2
學年 102
學期 2
發表日期 2014-05-07
作品名稱 Cluster-based Classification of Diabetic Nephropathy among Type 2
作品名稱(其他語言)
著者 Guan-Mau Huang; Yu-Chun Lee; Julia Tzu-Ya Weng; Yi-Cheng Chen; Lawrence Shih-Hsin Wu
作品所屬單位 資訊工程學系暨研究所
出版者
會議名稱 The 3rd International Congress on Natural Sciences and Engineering (ICNSE'14)
會議地點 Kyoto, Japan
摘要 The prevalence of type 2 diabetes is increasing at an alarming rate. Various complications are associated with type 2 diabetes, with diabetic nephropathy being the leading cause of renal failure among diabetics. Often, when patients are diagnosed with diabetic nephropathy, their renal functions have already been significantly damaged, speeding up the progression towards end stage renal disease. Therefore, a risk prediction tool may be beneficial for the implementation of early treatment and prevention. In the present study, we propose to develop a prediction model integrating clustering and classification approaches for the identification of diabetic nephropathy among type 2 diabetes patients. Clinical and genotyping data are obtained from 345 type 2 diabetic patients(160 with non-diabetic nephropathy and 185 with diabetic nephropathy). The performance of using clinical features alone for cluster-based classification is compared with that of utilizing a combination of clinical and genetic attributes. We find that the inclusion of genetic features yield better prediction results. Further refinement of the proposed approach has the potential to facilitate the accurate identification of diabetic nephropathy and the development of better treatment in a clinical setting.
關鍵字 type 2 diabetes diabetic nephropathy classification clustering genetic
語言 en_US
收錄於 EI
會議性質 國際
校內研討會地點
研討會時間 20140507~2014009
通訊作者 Julia Tzu-Ya Weng
國別 JPN
公開徵稿 Y
出版型式 電子版
出處 The 3rd International Congress on Natural Sciences and Engineering (ICNSE'14), pp. 861-867.
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