Gel electrophoresis of a charge-regulated, bi-functional particle
學年 101
學期 2
出版（發表）日期 2013-03-01
作品名稱 Gel electrophoresis of a charge-regulated, bi-functional particle
作品名稱（其他語言）
著者 Hsu, Jyh-Ping; Huang, Chih-Hua; Tseng, Shiojenn
單位 淡江大學數學學系
出版者 Weinheim: Wiley - V C H Verlag GmbH & Co. KGaA
著錄名稱、卷期、頁數 Electrophoresis 34(5), pp.785–791
摘要 Adopting a Brinkman fluid model, we analyzed the electrophoresis of a charged-regulated, bi-functional particle containing both acidic and basic functional groups in a gel solution. Both the long-range hydrodynamic effect arising from the liquid drag and the short-range steric effect from particle–polymer interaction are considered. The type of particle considered is capable of simulating both biocolloids such as microorganisms and cells, and particles with adsorbed polyelectrolyte or membrane layer. Our model describes successfully the experimental data in the literature. The presence of gel has the effect of reducing the particle mobility and alleviating double-layer polarization so that the particle behavior is less complicated than that in the case where gel is absent. On the other hand, both the quantitative and qualitative behaviors of a particle depend highly on solution pH and background salt concentration, yielding interesting and significant results. These results provide valuable information for both experimental data interpretation and electrophoresis devices design.
關鍵字 Brinkman fluid; Charge-regulated bi-functional particle; Double-layer polarization; Gel electrophoresis
語言 en_US
ISSN 0173-0835 1522-2683
期刊性質 國外
收錄於 SCI
產學合作
通訊作者 Hsu, Jyh-Ping
審稿制度
國別 DEU
公開徵稿
出版型式 紙本 電子版
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