Dynamic cell attachment of HepG2 in a microchannel
學年 101
學期 2
發表日期 2013-04-07
作品名稱 Dynamic cell attachment of HepG2 in a microchannel
作品名稱（其他語言）
著者 Yang, Lung-Jieh; Lu, Chieh-Wen; Liang, Jia-Chi; Han, Hsieh-Cheng
作品所屬單位 淡江大學機械與機電工程學系
出版者 Institute of Electrical and Electronics Engineers ( IEEE )
會議名稱 The 8th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (IEEE NEMS 2013)
會議地點 Suzhou, China
摘要 A dynamic filling experiment using PBS with HepG2 tumor cells is performed for observing the attachment behavior in capillaries. A PDMS microchannel mimicking the capillary blood vessel is fabricated by the soft lithography. With treating the PDMS microchannels by different plasmas, the corresponding surface roughness (Ra) data are experimentally measured by AFM. Using these PDMS microchannels well defined by proper Ra values, liquid streams with microbeads and living HepG2 tumor cells are filled in, respectively. The microbead and cell attachment areas in the PDMS microchannel have been recorded dynamically with 10 min interval. Finally, the authors qualitatively discussed the surface roughness effect on the particle or cell attachment in a PDMS microchannel.
關鍵字 microchannel;blood vessels;fractal;PDM
語言 en
收錄於
會議性質 國際
校內研討會地點
研討會時間 20130407~20130410
通訊作者 楊龍杰
國別 CHN
公開徵稿 Y
出版型式 紙本
出處 Proceedings of the 8th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (IEEE NEMS 2013), 4p.
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