Human aldehyde dehydrogenase E3 isozyme is a betaine aldehyde dehydrogenase
學年 84
學期 1
出版（發表）日期 1995-08-01
作品名稱 Human aldehyde dehydrogenase E3 isozyme is a betaine aldehyde dehydrogenase
作品名稱（其他語言）
著者 Chern, Ming-kai; Pietruszko, Regina
單位 淡江大學生命科學研究所
出版者 Maryland Heights: Academic Press
著錄名稱、卷期、頁數 Biochemical and Biophysical Research Communications 213(2), pp.561-568
摘要 The E3 isozyme of human aldehyde dehydrogenase (EC 1.2.1.3), with broad substrate specificity, which also catalyzes dehydrogenation of 4-aminobutyraldehyde, was purified and sequenced recently (1,3). It has been shown during this investigation to have betaine aldehyde dehydrogenase activity. Betaine aldehyde and 4-aminobutyraldehyde activities copurified on six chromatographic columns. Molecular properties of the homogeneous product were identical with those of E3 isozyme. Activity with betaine aldehyde was considerably higher than that with 4-aminobutyraldehyde, the best known substrate. Thus, human E3 isozyme and betaine aldehyde dehydrogenase (EC 1.2.1.8) are the same enzyme.
關鍵字
語言 en
ISSN 0006-291X
期刊性質 國外
收錄於
產學合作
通訊作者 Pietruszko, Regina
審稿制度
國別 USA
公開徵稿
出版型式 紙本
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