| B-form to S-form transition in a double-stranded DNA | |
|---|---|
| 學年 | 90 |
| 學期 | 2 |
| 發表日期 | 2002-02-01 |
| 作品名稱 | B-form to S-form transition in a double-stranded DNA |
| 作品名稱（其他語言） | |
| 著者 | 黎璧賢; 周子聰 |
| 作品所屬單位 | 淡江大學物理學系 |
| 出版者 | 東海大學物理學系 |
| 會議名稱 | 2002中華民國物理學會年匯暨研究成果發表會 |
| 會議地點 | 台中, 台灣 |
| 摘要 | When a DNA in its nature double-helical state is stretched by an external force, its length undergoes a sharp extension from the B-form to the 1.7 times elongated S-form. This phenomenon is investigated in the framework of a model of a double-stranded with basepair interactions and bending. Shape equations governing the structure of the DNA under external forces and torques are derived using a classical mechanical approach. The first-order nature of the B- to S-form transition is revealed clearly in terms of an effective potential with a barrier separating these two states. All the structural properties of the DNA in both forms can be calculated in detail. The configurations of the double strands, relative extension, amount of self-untwisting and the threshold stretching force of the DNA under stretched are obtained and compare well with experimental observations. |
| 關鍵字 | |
| 語言 | en |
| 收錄於 | |
| 會議性質 | 國內 |
| 校內研討會地點 | |
| 研討會時間 | 20020201~20020201 20020204~20020206 |
| 通訊作者 | |
| 國別 | TWN |
| 公開徵稿 | Y |
| 出版型式 | 紙本 |
| 出處 | 2002中華民國物理學會年匯暨研究成果發表會 |
| 相關連結 |
機構典藏連結 ( http://tkuir.lib.tku.edu.tw:8080/dspace/handle/987654321/69555 ) |
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