Membrane fouling mechanism and concentration effect in cross-flow microfiltration of BSA/dextran mixtures
學年 99
學期 1
出版（發表）日期 2011-01-01
作品名稱 Membrane fouling mechanism and concentration effect in cross-flow microfiltration of BSA/dextran mixtures
作品名稱（其他語言）
著者 Hwang, Kuo-Jen; Sz, Pan-Yu
單位 淡江大學化學工程與材料工程學系
出版者 Amsterdam: Elsevier BV
著錄名稱、卷期、頁數 Chemical Engineering Journal 166(2), pp.669–677
摘要 Membrane fouling in BSA/dextran binary suspension cross-flow microfiltration under various operating conditions is studied. The mechanisms for membrane fouling based on the SEM and CSLM observations under various suspension concentrations are proposed. BSA aggregates deposit onto the membrane surface while dextran molecules adsorb into the membrane pores, resulting in filtration resistances. The BSA deposition is mainly determined by the drag forces exerted on BSA aggregates on the membrane surface. Dextran adsorption is affected by the dextran concentration and applied pressure. The concentration effects on the filtration flux and filtration resistance are also discussed. The filtration fluxes for BSA/dextran mixtures are located between those for two pure substances and decrease with the increase in either the BSA or dextran concentration. However, the dextran concentration impact is more significant because the filtration resistance caused by membrane blocking is much higher than that caused by cake formation in most conditions. The filtration resistances due to concentration polarization, cake formation and membrane internal fouling can be estimated directly from the operating conditions using the semi-theoretical methods proposed in this study.
關鍵字 Cross-flow microfiltration; Membrane fouling; Membrane filtration; Bio-separation
語言 en
ISSN 1385-8947
期刊性質 國外
收錄於 SCI EI
產學合作
通訊作者 Hwang, Kuo-Jen
審稿制度
國別 NLD
公開徵稿
出版型式 紙本
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