Effect of air-sparging on the cross-flow microfiltration of microbe/protein bio-suspension
學年 99
學期 1
出版（發表）日期 2010-09-01
作品名稱 Effect of air-sparging on the cross-flow microfiltration of microbe/protein bio-suspension
作品名稱（其他語言）
著者 Hwang, Kuo-Jen; Chen, Ling
單位 淡江大學化學工程與材料工程學系
出版者 Amsterdam: Elsevier BV
著錄名稱、卷期、頁數 Journal of the Taiwan Institute of Chemical Engineers 41(5), pp.564–569
摘要 The effect of air-sparging on the performance of cross-flow microfiltration of microbe/protein bio-suspension is studied. A yeast/BSA binary suspension is separated using a two-parallel-plate cross-flow microfilter. The pseudo-steady filtration flux, cake properties and BSA rejection under various operating conditions are measured and discussed. The filtration flux increases with increasing filtration pressure, suspension and air velocities. The cake mass is significantly reduced by sparging air bubbles due to the increase in wall shear stress; however, this impact becomes trivial when air velocity exceeds 0.04 m/s. The average specific cake filtration resistance increases with increasing air velocity in a bubble flow, while suddenly decreases when the flow pattern changes to a slug flow. A drastic increase in BSA rejection is found as air bubbles are sparged into the filter channel. An increase in air flow velocity leads to higher BSA rejection especially in a slug flow regime. Taking filtration flux and BSA rejection into account, the BSA mass flux transported into filtrate decreases with increasing air velocity. Although sparging air bubbles can effectively enhance filtration flux, it is helpless for the separation of BSA from yeast cells. The results also indicate that the fluid flow pattern plays an important role in determining the filtration performance. The cake mass and BSA rejection in different flow regimes can be modeled using a force balance model for particle deposition and the standard capture equation for depth filtration, respectively.
關鍵字 Cross-flow microfiltration; Air-sparging; Cake properties; Protein rejection; Bio-separation
語言 en
ISSN 1876-1070
期刊性質 國外
收錄於 SCI EI
產學合作
通訊作者 Hwang, Kuo-Jen
審稿制度
國別 NLD
公開徵稿
出版型式 紙本
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