A Bayes regression approach to array-CGH data
學年 94
學期 2
出版（發表）日期 2006-05-01
作品名稱 A Bayes regression approach to array-CGH data
作品名稱（其他語言）
著者 溫啟仲; Wu, Y. J.; Huang, Y. H.; Chen, W. C.; Liu, S. C.; Jiang, S. S.
單位 淡江大學數學學系
出版者
著錄名稱、卷期、頁數 Statistical Applications in Genetics and Molecular Biology 5, pp.1-20
摘要 This paper develops a Bayes regression model having change points for the analysis of array-CGH data by utilizing not only the underlying spatial structure of the genomic alterations but also the observation that the noise associated with the ratio of the fluorescence intensities is bigger when the intensities get smaller. We show that this Bayes regression approach is particularly suitable for the analysis of cDNA microarray-CGH data, which are generally noisier than those using genomic clones. A simulation study and a real data analysis are included to illustrate this approach.
關鍵字
語言 en
ISSN 1544-6115 2194-6302
期刊性質 國外
收錄於
產學合作
通訊作者
審稿制度 否
國別 DEU
公開徵稿
出版型式 ,電子版,紙本
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