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標題:幾丁聚醣複合薄膜的製備與抗菌測試
學年
學期
發表日期2003/09/26
作品名稱幾丁聚醣複合薄膜的製備與抗菌測試
作品名稱(其他語言)Preparation and Antibacterial Test of Chitosan/PEGDA/PAA Composite Membrane
著者董崇民; Don, Trong-ming; 李志剛; 鄭廖平; 陳慶鐘; Chen, Ching-chung
作品所屬單位
出版者
會議名稱2003幾丁質幾丁聚醣研討會與年會=2003 Taiwan Chitin Chitosan Symposium & Agenda of Society Annual Meeting
會議地點苗栗縣, 臺灣
摘要本研究係利用含有二感光性官能基之寡聚物PEGDA、丙烯酸(Acrylic acid)單體及光起始劑之感光組成物塗佈於不同基材後,加以紫外光硬化處理形成薄膜。進一步,將幾丁聚醣溶於丙烯酸水溶液中並均勻塗佈於薄膜上,其中丙烯酸能發揮偶合劑之效用,擴散至薄膜中使幾丁聚醣植於薄膜表面。藉由控制幾丁聚醣之濃度使表層幾丁聚醣厚度達到奈米層級,因幾丁聚醣具有抗菌效果,故可製備出奈米級之抗菌複合薄膜。利用電子顯微鏡(FESEM)、接觸角(Contact angle)測試及 X射線光電子分析儀(ESCA)來作表面分析,並使用大腸桿菌Escherichia coli.及金黃色葡萄球菌Staphylococcus aureus來作抗菌測試。;Dopes prepared by blending of polyethylene glycol diacrylate (PEGDA), acrylic acid and a photoinitiator were cast and then UV cured on various substrates to form dense membranes. Subsequently, the later was coated with a layer of solution composed of chitosan, acrylic acid and water. As the acrylic acid diffused into the underneath membrane, chitosan coagulated into a nano-layer on the top. The morphology of the formed composite membrane was observed by low voltage FESEM. The contact angle measurement indicates a top surface consisted of high proportion of chitosan. The antibacterial activities of the membranes were examined with respect to a gram-negative (Escherichia coli) and a gram-positive bacteria (Staphylococcus aureus).
關鍵字幾丁聚醣;複合膜;抗菌活性測試;聚乙二醇二丙烯酸酯;聚丙烯酸;Chitosan;Composite Membrane;Antibacterial Activity Test;Polyethylene Glycol Diacrylate;Polyacrylic Acid
語言中文
收錄於
會議性質國內
校內研討會地點
研討會時間20030926~20030926
通訊作者
國別中華民國
公開徵稿Y
出版型式紙本
出處2003幾丁質幾丁聚醣研討會與年會大會手冊論文集=Proceedings of 2003 Taiwan Chitin Chitosan Symposium & Agenda of Society Annual Meeting,頁172-175
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