| Functional Dihydro-1H-imidazole Derivatives for MALDI Signal Enhancement of a Lysine-Specific Chemical Modification | |
|---|---|
| 學年 | 97 |
| 學期 | 1 |
| 出版（發表）日期 | 2009-01-01 |
| 作品名稱 | Functional Dihydro-1H-imidazole Derivatives for MALDI Signal Enhancement of a Lysine-Specific Chemical Modification |
| 作品名稱（其他語言） | |
| 著者 | Ho, Ming-yi; Shieh, Yu-tse; Liao, Chung-lin; Chen, Yau-hung; Cheng, Chien-chung |
| 單位 | 淡江大學生命科學研究所 |
| 出版者 | 臺北市：中國化學學會 |
| 著錄名稱、卷期、頁數 | Journal of the Chinese Chemical Society 56(5), pp.987-994 |
| 摘要 | The preparation of 2-methoxy-4,5-dihydro-1H-imidazole (MeO-DHIM) was accomplished by one-step synthesis of O-methyl-isourea. The signal enhancement induced by these attached moieties increases in an order of compound 1 ≈ 4 < 2 < 5 ≈ 6 < 3 in MALDI mass spectrometry. Peptide-compound 3 adduct was approximately 20 times signal enhancement of the unmodified peptide. |
| 關鍵字 | |
| 語言 | en_US |
| ISSN | 0009-4536 |
| 期刊性質 | 國內 |
| 收錄於 | SCI |
| 產學合作 | |
| 通訊作者 | Chen, Yau-hung |
| 審稿制度 | 否 |
| 國別 | TWN |
| 公開徵稿 | |
| 出版型式 | ,紙本 |
| 相關連結 |
機構典藏連結 ( http://tkuir.lib.tku.edu.tw:8080/dspace/handle/987654321/42006 ) |
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