教師資料查詢 | 類別: 期刊論文 | 教師: 陳曜鴻 CHEN, YAU-HUNG (瀏覽個人網頁)

標題:Myogenic regulatory factors Myf5 and Mrf4 of fish: current status and perspective
學年
學期
出版(發表)日期2008/12/01
作品名稱Myogenic regulatory factors Myf5 and Mrf4 of fish: current status and perspective
作品名稱(其他語言)
著者陳曜鴻; Chen, Yau-hung; Tsai, H. J.
單位淡江大學化學學系
出版者Wiley-Blackwell
著錄名稱、卷期、頁數Journal of Fish Biology 73(8), pp.1872-1890
摘要Recent advances in the understanding of fish myogenic regulatory factors (MRF) are described in this review. Specifically, two of the MRFs are discussed, Myf5 and Mrf4, which are encoded by a highly linked gene loci ( mrf4 and myf5) that is conserved among vertebrates. Experiments related to the expression patterns, biological functions and regulatory network of mrf4 and myf5 are highlighted, and examples of gene organizations and protein features among known vertebrate species are outlined. Furthermore, the complicated regulatory mechanisms of myf5 are discussed using zebrafish Danio rerio as a model. Multiple regulatory elements that control the specific expression of zebrafish myf5 are elucidated, including enhancer, silencer, proximal and distal elements, the interaction between proximal regulatory cassette −82/−62 and its cognate binding transcription factors, and a plausible post-transcriptional regulatory mechanism. This review article highlights a fundamental molecular mechanism of mrf4 and myf5 during fish muscle development.
關鍵字
語言英文
ISSN0022-1112
期刊性質國外
收錄於
產學合作
通訊作者
審稿制度
國別英國
公開徵稿
出版型式,紙本
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