Metal Ion Dependent Binding and Nuclease Activity of Hexaazacyclophane | |
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學年 | 84 |
學期 | 2 |
出版(發表)日期 | 1996-02-01 |
作品名稱 | Metal Ion Dependent Binding and Nuclease Activity of Hexaazacyclophane |
作品名稱(其他語言) | |
著者 | Wang, Wen-jwu |
單位 | 淡江大學化學學系 |
出版者 | 中國化學會 |
著錄名稱、卷期、頁數 | Journal of the Chinese Chemical Society 43(1), p.72-75 |
摘要 | The HAPP-Fe complex was more active than HAPP-Cu complex in cleavage of DNA in the presence of dithiothreitol and hydrogen peroxide. In contrast, the HAPP-Cu complex was found to bind more strongly with λ-DNA, whereas the HAPP-Fe binds weakly. It was shown that the metal ion complexed with HAPP ligand can influence the binding and cleaving activity due to the ability of the ligand to undergo geometrical tautomerization. |
關鍵字 | HAPP-Cu;HAPP-Fe;DNA binding affinity;DNA cleavage |
語言 | en |
ISSN | 0009-4536 |
期刊性質 | 國內 |
收錄於 | |
產學合作 | |
通訊作者 | |
審稿制度 | 否 |
國別 | TWN |
公開徵稿 | |
出版型式 | ,電子版 |
相關連結 |
機構典藏連結 ( http://tkuir.lib.tku.edu.tw:8080/dspace/handle/987654321/25050 ) |