Metal Ion Dependent Binding and Nuclease Activity of Hexaazacyclophane
學年 84
學期 2
出版(發表)日期 1996-02-01
作品名稱 Metal Ion Dependent Binding and Nuclease Activity of Hexaazacyclophane
作品名稱(其他語言)
著者 Wang, Wen-jwu
單位 淡江大學化學學系
出版者 中國化學會
著錄名稱、卷期、頁數 Journal of the Chinese Chemical Society 43(1), p.72-75
摘要 The HAPP-Fe complex was more active than HAPP-Cu complex in cleavage of DNA in the presence of dithiothreitol and hydrogen peroxide. In contrast, the HAPP-Cu complex was found to bind more strongly with λ-DNA, whereas the HAPP-Fe binds weakly. It was shown that the metal ion complexed with HAPP ligand can influence the binding and cleaving activity due to the ability of the ligand to undergo geometrical tautomerization.
關鍵字 HAPP-Cu;HAPP-Fe;DNA binding affinity;DNA cleavage
語言 en
ISSN 0009-4536
期刊性質 國內
收錄於
產學合作
通訊作者
審稿制度
國別 TWN
公開徵稿
出版型式 ,電子版
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