Antitumor agents. CII. hinokiflavone, a cytotoxic principle from Rhus succedanea and the cytotoxicity of the related biflavanoids
學年 77
學期 1
出版(發表)日期 1989-01-01
作品名稱 Antitumor agents. CII. hinokiflavone, a cytotoxic principle from Rhus succedanea and the cytotoxicity of the related biflavanoids
作品名稱(其他語言)
著者 Lin, Y. M.; 陳發清; Chen, F. C.; Lee, K. H.
單位 淡江大學化學學系
出版者 Stuttgart: Georg Thieme Verlag
著錄名稱、卷期、頁數 Planta medica 55(2), pp.166-168
摘要 Hinokiflavone (1) was isolated as the cytotoxic principle from the drupes of Rhus succedanea L. A comparison of the cytotoxicity of 1 and other related biflavonoids, including amentoflavone (2), robustaflavone (3), agathisflavone (4), rhusflavone (5), rhusflavanone (6) and its hexaacetate (7), succedaneaflavanone (8) and its hexaacetate (9), cupressuflavone (10), neorhusflavanone (11), volkensiflavone (12) and its hexamethyl ether (13), spicataside (14) and its nonaacetate (15), morelloflavone (16) and its heptaacetate (17) and heptamethyl ether (18), GB-1a (19) and its hexamethyl ether (20) and 7″-O-β-glucoside (21), and GB-2a (22), indicates that an ether linkage between two units of apigenin as seen in 1 is structurally required for significant cytotoxicity. Compounds 13 and 20 also demonstrated significant cytotoxicity.
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語言 en
ISSN 0032-0943
期刊性質 國外
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國別 DEU
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出版型式 紙本
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