| Synthesis of β-Amino and β-Methoxy Ketones by Lewis Acids Promoted β-Substitution Reactions of β,γ-Unsaturated Ketones | |
|---|---|
| 學年 | 92 |
| 學期 | 1 |
| 出版（發表）日期 | 2003-12-01 |
| 作品名稱 | Synthesis of β-Amino and β-Methoxy Ketones by Lewis Acids Promoted β-Substitution Reactions of β,γ-Unsaturated Ketones |
| 作品名稱（其他語言） | |
| 著者 | Lee, Adam Shih-yuan; Wang, Shu-huei; Chang, Yu-ting; Chu, Shu-fang |
| 單位 | 淡江大學化學學系 |
| 出版者 | Stuttgart: Georg Thieme Verlag |
| 著錄名稱、卷期、頁數 | Synlett 2003(15), pp.2359-2363 |
| 摘要 | A reaction mixture of β,γ-unsaturated ketone and BF3·OEt2 in CH3OH was stirred at room temperature and β-methoxy ketone was produced in high yield. The β-amino ketone was obtained as the major product from a reaction mixture of β,γ-unsaturated ketone, AlCl3 and Ts-NH2 in CH2Cl2 at room temperature. This Lewis acid promoted β-substitution reaction mechanism was proposed as that the process occurred via in situ isomerization of β,γ-unsaturated ketone to α,β-unsaturated ketone followed by the 1,4-addition reaction. |
| 關鍵字 | β,γ-unsaturated ketone; β-amino ketone; β-methoxy ketone; α,β-unsaturated ketone; 1,4-addition reaction |
| 語言 | en |
| ISSN | 0936-5214 |
| 期刊性質 | 國外 |
| 收錄於 | SCI |
| 產學合作 | |
| 通訊作者 | |
| 審稿制度 | |
| 國別 | DEU |
| 公開徵稿 | |
| 出版型式 | 紙本 |
| 相關連結 |
機構典藏連結 ( http://tkuir.lib.tku.edu.tw:8080/dspace/handle/987654321/25304 ) |
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