| Synthesis of a New Family of Aminocyclitols from D-(-)-Quinic acid | |
|---|---|
| 學年 | 96 |
| 學期 | 1 |
| 出版（發表）日期 | 2008-01-01 |
| 作品名稱 | Synthesis of a New Family of Aminocyclitols from D-(-)-Quinic acid |
| 作品名稱（其他語言） | |
| 著者 | Shih, Tzenge-lien; Li, Heng-Yi; Ke, Ming-Shin; Kuo, Wei-Shen |
| 單位 | 淡江大學化學學系 |
| 出版者 | Philadelphia: Taylor & Francis Inc. |
| 著錄名稱、卷期、頁數 | Synthetic Communications 38(23), pp.4139-4149 |
| 摘要 | In continuation of our interest in the synthesis of glycosidase inhibitors, we report herein an efficient synthesis of three new polyhydroxylated amino cyclohexane derivatives (aminocyclitols) that may potentially possess important biological activities. The key step involved the highly stereoselective dihydroxylation of protected azido cyclohexene derivatives 5, 9, and 15, which were easily red from D-(-)-quinic acid. The subsequent hydrogenation step was conducted under acidic conditions to provide the target molecules in an efficient manner with high overall yields. |
| 關鍵字 | |
| 語言 | en |
| ISSN | 0039-7911; 1532-2432 |
| 期刊性質 | 國外 |
| 收錄於 | SCI |
| 產學合作 | |
| 通訊作者 | |
| 審稿制度 | |
| 國別 | USA |
| 公開徵稿 | |
| 出版型式 | 紙本 |
| 相關連結 |
機構典藏連結 ( http://tkuir.lib.tku.edu.tw:8080/dspace/handle/987654321/25302 ) |
| SDGS | 良好健康和福祉,優質教育 |
GoogleAnalytics