2-D ultrasound strain images for breast cancer diagnosis using nonrigid subregion registration
學年 94
學期 2
出版(發表)日期 2006-06-01
作品名稱 2-D ultrasound strain images for breast cancer diagnosis using nonrigid subregion registration
著者 Chii-Jen Chen; Ruey-F Chang; Woo Kyung Moon; Dar-Ren Chen; Wu; Hwa-Koon
著錄名稱、卷期、頁數 Ultrasound in Medicine and Biology 32(6), p.837-846
摘要 Tissue elasticity of a lesion is a useful criterion for the diagnosis of breast ultrasound (US). Elastograms are created by comparing ultrasonic radio-frequency waveforms before and after a light-tissue compression. In this study, we evaluate the accuracy of continuous US strain image in the classification of benign from malignant breast tumors. A series of B-mode US images is applied and each case involves 60 continuous images obtained by using the steady artificial pressure of the US probe. In general, after compression by the US probe, a soft benign tumor will become flatter than a stiffened malignant tumor. We proposed a computer-aided diagnostic (CAD) system by utilizing the nonrigid image registration modality on the analysis of tumor deformation. Furthermore, we used some image preprocessing methods, which included the level set segmentation, to improve the performance. One-hundred pathology-proven cases, including 60 benign breast tumors and 40 malignant tumors, were used in the experiments to test the classification accuracy of the proposed method. Four characteristic values—normalized slope of metric value (NSM), normalized area difference (NAD), normalized standard deviation (NSD) and normalized center translation (NCT)—were computed for all cases. By using the support vector machine, the accuracy, sensitivity, specificity and positive and negative predictive values of the classification of continuous US strain images were satisfactory. The Az value of the support vector machine based on the four characteristic values used for the classification of solid breast tumors was 0.9358.
關鍵字 Strain;Ultrasound;Level set;Image registration;Nonrigid registration;Subregion registration
語言 en_US
ISSN 1879-291X;0301-5629
期刊性質 國外
國別 USA
出版型式 ,電子版,紙本

機構典藏連結 ( http://tkuir.lib.tku.edu.tw:8080/dspace/handle/987654321/122979 )

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