|標題：Associations Between Lifestyle Factors and Reduced Kidney Function in US Older Adults: NHANES 1999–2016|
|作品名稱||Associations Between Lifestyle Factors and Reduced Kidney Function in US Older Adults: NHANES 1999–2016|
|著者||Horng-Jinh Chang; Kuan-Reng Lin; Meng-Te Lin; Junn-Liang Chang|
|著錄名稱、卷期、頁數||International Journal of Public Health,66,p.1-9|
|摘要||Objective: This study aimed to evaluate the associations between lifestyle factors and the
estimated glomerular filtration rate (eGFR) levels in older adults by analyzing the
United States National Health and Nutrition Examination Survey data (1999–2016).
Methods: A total of 10,052 eligible participants were divided into two groups: reduced
eGFR group (eGFR < 60 ml/min/1.73 m2
) and normal group (eGFR ≥ 60 ml/min/1.73 m2
The primary factors were physical activity, alcohol consumption, smoking, and
Results: Multivariable analysis revealed that older age, proteinuria, cardiovascular disease,
diabetes, hyperuricemia, and hypertension were significantly associated with higher odds of
reduced kidney function. Sufficient physical activity, current alcohol consumption, and being a
current smoker were significantly associated with lower odds of reduced kidney function.
However, subgroup analysis by sex revealed that the effects of proteinuria, current alcohol
consumption, and sufficient physical activity were sex-specific.
Conclusion: Several risk and beneficial factors for reduced kidney function in adults aged
65 and above in the United States were identified, but some of them might be sex-specific.
Further studies are warranted to confirm these findings in other populations and countries
|關鍵字||chronic kidney disease;estimated glomerular filtration rate;exercise;kidney function;risk factors|