Synthesis of Silica-coated Gold Nanorod as Raman Tags by Modulating Cetyltrimethylammonium Bromide Concentration
學年 100
學期 2
出版（發表）日期 2012-06-16
作品名稱 Synthesis of Silica-coated Gold Nanorod as Raman Tags by Modulating Cetyltrimethylammonium Bromide Concentration
作品名稱（其他語言）
著者 Chia-Chi Huang; Chen-Han Huang; I-Ting Kuo; Lai-Kwan Chau; Tzzy-Schiuan Yang
單位
出版者
著錄名稱、卷期、頁數 Colloids and Surfaces A: Physicochemical and Engineering Aspects 40, p.61-68
摘要 The applications of colloidal gold nanorods (AuNRs) as substrate for surface-enhanced Raman scattering (SERS) inevitably have to deal with a bilayer of cetyltrimethylammonium bromide (CTAB) around the AuNR surface. Here, we report an improved fabrication of silica-coated gold nanorods as SERS tags by mainly controlling the amount of CTAB to facilitate the synthesis. CTAB molecules on AuNRs were partially removed by centrifugation twice to allow the adsorption of Raman marker molecules and were re-added to promote the growth of silica shells. The zeta potential was used to monitor the charge state of AuNRs during the synthesis. A model of the morphology changes of CTAB assemblies is proposed based on the measurement of zeta potential and effects of pH value and CTAB/TEOS molar ratio. SERS tags with single AuNR enclosed in a round and 40 nm-thick silica shell were produced within 24 h. The SERS signal of a thus-prepared tag was compared with that of a nanoaggregate tag by a model probe–target system made of a biotin-functionalized polystyrene (PS) microsphere. Results showed that the SERS signal from the streptavidin-functionalized AuNR tag on a single PS microsphere is comparable to that from the nanoaggregate-tag counterpart.
關鍵字 Raman tag;Au nanorod;Direct silica coating;Surface-enhanced Raman scattering;Cationic surfactant
語言 en_US
ISSN 1873-4359
期刊性質 國外
收錄於 SCI
產學合作
通訊作者
審稿制度 是
國別 NLD
公開徵稿
出版型式 ,電子版
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