教師資料查詢 | 類別: 期刊論文 | 教師: 張玉坤 Yue-cune Chang (瀏覽個人網頁)

標題:A Web-Based Self-Titration Program to Control Blood Pressure in Patients With Primary Hypertension: Randomized Controlled Trial
學年108
學期1
出版(發表)日期2019/12/01
作品名稱A Web-Based Self-Titration Program to Control Blood Pressure in Patients With Primary Hypertension: Randomized Controlled Trial
作品名稱(其他語言)
著者Chi-Wen Kao; Ting-Yu Chen; Shu-Meng Cheng; Wei-Shiang Lin; Yue-Cune Chang
單位
出版者
著錄名稱、卷期、頁數Journal of Medical Internet Research 21 (12), e15836
摘要Background: Hypertension is a major cause of mortality in cardiac, vascular, and renal disease. Effective control of elevated
blood pressure has been shown to reduce target organ damage. A Web-based self-titration program may empower patients to
control their own disease, share decisions about antihypertensive dose titration, and improve self-management, ultimately improving
health-related quality of life.
Objective: Our primary aim was to evaluate the effects of a Web-based self-titration program for improving blood pressure
control in patients with primary hypertension. Our secondary aim was to evaluate the effects of that program on improving
health-related quality of life.
Methods: This was a parallel-group, double-blind, randomized controlled trial with assessments at baseline, 3 months, and 6
months. We included patients with primary hypertension (blood pressure>130/80 mm Hg) from a cardiology outpatient department
in northern Taiwan and divided them randomly into intervention and control groups. The intervention group received the Web-based
self-titration program, while the control group received usual care. The random allocation was concealed from participants and
outcome evaluators. Health-related quality of life was measured by the EuroQol five-dimension self-report questionnaire. We
used generalized estimating equations to evaluate the effects of the intervention.
Results: We included 222 patients and divided them equally into intervention (n=111) and control (n=111) groups. Patients
receiving the Web-based self-titration program showed significantly greater improvement in the systolic and diastolic blood
pressure control than those who did not receive this program, at 3 months (–21.4 mm Hg and –5.4 mm Hg, respectively; P<.001)
and 6 months (–27.8 mm Hg and –9.7 mm Hg, respectively; P<.001). Compared with the control group, the intervention group
showed a significant decrease in the overall defined daily dose at both 3 (–0.202, P=.003) and 6 (–0.236, P=.001) months. Finally,
health-related quality of life improved significantly in the intervention group compared with the control group at both 3 and 6
months (both, P<.001).
Conclusions: A Web-based self-titration program can provide immediate feedback to patients about how to control their blood
pressure and manage their disease at home. This program not only decreases mean blood pressure but also increases health-related
quality of life in patients with primary hypertension.
關鍵字Web-based;self-titration; blood pressure;hypertension;health-related quality of life
語言英文
ISSN1439-4456
期刊性質國外
收錄於SCI;
產學合作
通訊作者
審稿制度
國別加拿大
公開徵稿
出版型式,電子版
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