教師資料查詢 | 類別: 期刊論文 | 教師: 蔡志群 Chih-chun Tsai (瀏覽個人網頁)

標題:A Fourfold Increase of Oesophageal Variceal Bleeding in Cirrhotic Patients with a History of Oesophageal Variceal Bleeding
學年104
學期1
出版(發表)日期2016/01/01
作品名稱A Fourfold Increase of Oesophageal Variceal Bleeding in Cirrhotic Patients with a History of Oesophageal Variceal Bleeding
作品名稱(其他語言)
著者Tsung-Hsing Hung; Chih-Wei Tseng; Chih-Chun Tsai; Chorng-Jang Lay; Chen-Chi Tsai
單位
出版者
著錄名稱、卷期、頁數Singapore Medical Journal 57(9), p.511-513
摘要INTRODUCTION
Large, recent population-based data for evaluating the predictors of oesophageal variceal bleeding (OVB) among cirrhotic patients is still lacking. This study aimed to determine the cumulative incidence of OVB among cirrhotic patients and identify the predictors of OVB occurrence.

METHODS
Patient information on 38,172 cirrhotic patients without a history of OVB, who were discharged between 1 January 2007 and 31 December 2007, was obtained from the Taiwan National Health Insurance Database for this study. All patients were followed up for three years. Death was the competing risk when calculating the cumulative incidences and hazard ratios (HRs) of OVB.

RESULTS
OVB was present in 2,609 patients (OVB group) and absent in 35,563 patients (non-OVB group) at hospitalisation. During the three-year follow-up period, the cumulative incidence of OVB was 44.5% and 11.3% in the OVB and non-OVB group, respectively (p < 0.001). Modified Cox regression analysis showed that the HR of OVB history was 4.42 for OVB occurrence (95% confidence interval [CI] 4.13–4.74). Other predictors for OVB occurrence included hepatocellular carcinoma (HR 1.16, 95% CI 1.09–1.24), young age (HR 0.98, 95% CI 0.98–0.98), ascites (HR 1.46, 95% CI 1.37–1.56), alcohol-related disorders (HR 1.20, 95% CI 1.12–1.28), peptic ulcer bleeding (HR 1.26, 95% CI 1.13–1.41) and diabetes mellitus (HR 1.14, 95% CI 1.06–1.23).

CONCLUSION
Cirrhotic patients have a fourfold increased risk of future OVB following the first incidence of OVB.
關鍵字cirrhosis;epidemiology;oesophageal variceal bleeding;portal hypertension
語言英文
ISSN0037-5675
期刊性質國外
收錄於SCI;
產學合作
通訊作者
審稿制度
國別新加坡
公開徵稿
出版型式,紙本
相關連結
Google+ 推薦功能,讓全世界都能看到您的推薦!