教師資料查詢 | 類別: 期刊論文 | 教師: 施增廉 SHIH, TZENGE-LIEN (瀏覽個人網頁)

標題:Synthesis of Novel Isoquinolino[5,4-ab]phenanthridine Derivatives via Pictet–Spengler Reaction
學年107
學期2
出版(發表)日期2019/03/03
作品名稱Synthesis of Novel Isoquinolino[5,4-ab]phenanthridine Derivatives via Pictet–Spengler Reaction
作品名稱(其他語言)
著者Tsai, Min-Chen; Huang, Pei Yu; Syu, Liang Sheng; Shih, Tzenge-Lien
單位
出版者
著錄名稱、卷期、頁數Synthesis 51(6), pp.1377-1382
摘要The reaction of 5-amino-2-[2 (dimethylamino)ethyl]-6-phenyl-1H-benzo[de]isoquinoline-1,3(2H)-dione with a series of aldehydes in acidic media (phosphoric acid, trifluoromethanesulfonic acid, and trifluoroacetic acid) is described. This key step is based on the Pictet–Spengler reaction to synthesize ten novel isoquinolino[5,4-ab]phenanthridine derivatives. The most effective acid is phosphoric acid and optimized yields were obtained. The frameworks of target compounds are unique and have never been reported.
關鍵字homophthalimide;isoquinoline-1,3-dione;naphthalimide ;phenanthridine;Pictet;Spengler reaction;Suzuki–Miyaura cross-coupling reaction
語言英文
ISSN1377-1382
期刊性質國外
收錄於SCI;
產學合作
通訊作者
審稿制度
國別德國
公開徵稿
出版型式,電子版
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