Diffusiophoresis of a pH-regulated polyelectrolyte in a nanopore of nonuniform cross section
學年 104
學期 1
出版(發表)日期 2015-09-30
作品名稱 Diffusiophoresis of a pH-regulated polyelectrolyte in a nanopore of nonuniform cross section
作品名稱(其他語言)
著者 Chun-Yuan Su; Jyh-Ping Hsu; Shiojenn Tseng
單位
出版者
著錄名稱、卷期、頁數 Microfluid Nanofluid 19(3), p.647-652
摘要 The diffusiophoresis of a pH-regulated polyelectrolyte (PE) along the axis of a charged nanopore having nonuniform cross section is modeled, aimed with improving the performance of a nanopore-based sensing device for single biomolecules such as DNAs and proteins. Previous analysis based on a rigid particle of constant charge density in a solution containing binary ionic species is extended to a porous, pH-regulated PE in a solution containing multiple ionic species so that the conditions considered are much closer to reality. The behavior of the PE under various conditions is simulated by varying its charge, relative size, position in the nanopore, the solution pH, and the background salt concentration. We show that the PE translocation velocity can be regulated by the pore width and its charged conditions. In particular, both the magnitude and the direction of the translocation velocity can be adjusted.
關鍵字 Local Electric Field;Throat Region;Single Biomolecule;Translocation Velocity;Constant Charge Density
語言 en
ISSN
期刊性質 國外
收錄於 SCI
產學合作
通訊作者 Jyh-Ping Hsu; Shiojenn Tseng
審稿制度
國別 DEU
公開徵稿
出版型式 ,電子版,紙本
相關連結

機構典藏連結 ( http://tkuir.lib.tku.edu.tw:8080/dspace/handle/987654321/115575 )