教師資料查詢 | 類別: 期刊論文 | 教師: 王三郎 WANG SAN-LANG (瀏覽個人網頁)

標題:Reclamation of shrimp heads for the production of α-glucosidase inhibitors by Staphylococcus sp. TKU043
學年107
學期1
出版(發表)日期2018/08/01
作品名稱Reclamation of shrimp heads for the production of α-glucosidase inhibitors by Staphylococcus sp. TKU043
作品名稱(其他語言)
著者San-Lang Wang; Yu-Cheng Su; Van Bon Nguyen; Anh Dzung Nguyen
單位
出版者
著錄名稱、卷期、頁數Research on Chemical Intermediates 44(3), 9 pages
摘要Alpha-glucosidase inhibitors (aGIs) have received much attention due to
their important use in treating diabetes mellitus. Although some synthetic aGIs have
been available for a long time, they often cause various unexpected side effects. The
purpose of this study was to reclaim shrimp heads for the production of aGIs via
bacteria. Staphylococcus sp. TKU043, a bacterium strain isolated from Taiwanese
soil produced aGIs in a shrimp-head-containing medium. Maximum productivity of
aGIs (1457 U/mL) was found after cultivation in 1% shrimp head powder medium
for 3 days. The aGI partially purified by column chromatography showed thermal
instability, and presumably was a proteinous material. The inhibitor mode of this
aGI was determined to be a mixed inhibition mode (non-competitive–uncompetitive
inhibition).
關鍵字Chitin;Shrimp head;α-glucosidase inhibitor;Staphylococcus
語言英文
ISSN0922-6168
期刊性質國外
收錄於SCI;
產學合作
通訊作者Wang SL; Su YC, Nguyen VB; Nguyen AD
審稿制度
國別美國
公開徵稿
出版型式,電子版
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