教師資料查詢 | 類別: 期刊論文 | 教師: 李世元 ADAM SHIH-YUAN LEE (瀏覽個人網頁)

標題:Synthesis of 3-Substituted Indole by AlCl3 Promoted Reaction of α,β-Unsaturated Ketone with Indole
學年102
學期2
出版(發表)日期2014/06/10
作品名稱Synthesis of 3-Substituted Indole by AlCl3 Promoted Reaction of α,β-Unsaturated Ketone with Indole
作品名稱(其他語言)
著者Adam Shih-Yuan Lee, Yu-Chi Wu, Yu-Ting Chang and Bo-Cheng
單位
出版者
著錄名稱、卷期、頁數Research on Chemical Intermediates
摘要A one-pot Lewis acid-promoted reaction condition of β,γ-unsaturated ketone with indole was developed for the synthesis of 3-substituted indoles with moderate to good yields. A Lewis acid such as AlCl3 was shown to be a promising promoter for in situ isomerization of β,γ-unsaturated ketone to its corresponding α,β-unsaturated ketone, then undergoing Friedel–Crafts Michael addition reaction with indole to afford 3-substituted indole.
關鍵字Friedel–Crafts reaction Michael reaction; 3-Substituted indole; β,γ-Unsaturated ketone; α,β-Unsaturated ketone
語言英文(美國)
ISSN
期刊性質國外
收錄於SCI;
產學合作
通訊作者Adam Shih-Yuan Lee
審稿制度
國別美國
公開徵稿
出版型式,電子版,紙本
相關連結
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