Nickel Catalyzed Highly Chemo- and Stereoselectively Borylative Cyclization of 1,6-Enynes with Bis(pinacolato)diboron
學年 105
學期 2
出版（發表）日期 2017-05-17
作品名稱 Nickel Catalyzed Highly Chemo- and Stereoselectively Borylative Cyclization of 1,6-Enynes with Bis(pinacolato)diboron
作品名稱（其他語言）
著者 Jen-Chieh Hsieh; Ya-Chun Hong; Chun-Ming Yang; Subramaniyan Mannathanb; Chien-Hong Cheng
單位
出版者
著錄名稱、卷期、頁數 Organic Chemistry Frontiers 4, p.1615–1619
摘要 A highly chemo- and stereoselective nickel-catalyzed borylative cyclization of 1,6-enynes with bis(pinacolato)diboron is described. Enynes containing an electron-deficient alkene such as a vinyl ketone provided alkenylboronates while enynes containing a terminal alkene gave homoallylic boronates. A plausible mechanism involving a nickelacyclopentene intermediate is proposed. In addition, the resulted alkenyl- or homoallylic boronates can be transformed to the corresponding ketones and alcohols via oxidation. Application to a palladium-catalyzed cross coupling reaction of alkenylboronates with aromatic halides has been demonstrated as well.
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語言 en
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期刊性質 國外
收錄於 SCI
產學合作
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審稿制度 是
國別 GBR
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出版型式 ,電子版,紙本
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機構典藏連結 ( http://tkuir.lib.tku.edu.tw:8080/dspace/handle/987654321/113426 )