| 標題：Nickel Catalyzed Highly Chemo- and Stereoselectively Borylative Cyclization of 1,6-Enynes with Bis(pinacolato)diboron |
|---|
| 學年 | 105 |
|---|
| 學期 | 2 |
|---|
| 出版（發表）日期 | 2017/05/17 |
|---|
| 作品名稱 | Nickel Catalyzed Highly Chemo- and Stereoselectively Borylative Cyclization of 1,6-Enynes with Bis(pinacolato)diboron |
|---|
| 作品名稱（其他語言） | |
|---|
| 著者 | Jen-Chieh Hsieh; Ya-Chun Hong; Chun-Ming Yang; Subramaniyan Mannathanb; Chien-Hong Cheng |
|---|
| 單位 | |
|---|
| 出版者 | |
|---|
| 著錄名稱、卷期、頁數 | Organic Chemistry Frontiers 4, p.1615–1619 |
|---|
| 摘要 | A highly chemo- and stereoselective nickel-catalyzed borylative cyclization of 1,6-enynes with bis(pinacolato)diboron is described. Enynes containing an electron-deficient alkene such as a vinyl ketone provided alkenylboronates while enynes containing a terminal alkene gave homoallylic boronates. A plausible mechanism involving a nickelacyclopentene intermediate is proposed. In addition, the resulted alkenyl- or homoallylic boronates can be transformed to the corresponding ketones and alcohols via oxidation. Application to a palladium-catalyzed cross coupling reaction of alkenylboronates with aromatic halides has been demonstrated as well. |
|---|
| 關鍵字 | |
|---|
| 語言 | 英文 |
|---|
| ISSN | |
|---|
| 期刊性質 | 國外 |
|---|
| 收錄於 | SCI; |
|---|
| 產學合作 | |
|---|
| 通訊作者 | |
|---|
| 審稿制度 | 是 |
|---|
| 國別 | 英國 |
|---|
| 公開徵稿 | |
|---|
| 出版型式 | ,電子版,紙本 |
|---|
| 相關連結 | |
|---|
|
Google+ 推薦功能，讓全世界都能看到您的推薦！
