標題:Nickel Catalyzed Highly Chemo- and Stereoselectively Borylative Cyclization of 1,6-Enynes with Bis(pinacolato)diboron |
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學年 | 105 |
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學期 | 2 |
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出版(發表)日期 | 2017/05/17 |
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作品名稱 | Nickel Catalyzed Highly Chemo- and Stereoselectively Borylative Cyclization of 1,6-Enynes with Bis(pinacolato)diboron |
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作品名稱(其他語言) | |
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著者 | Jen-Chieh Hsieh; Ya-Chun Hong; Chun-Ming Yang; Subramaniyan Mannathanb; Chien-Hong Cheng |
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單位 | |
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出版者 | |
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著錄名稱、卷期、頁數 | Organic Chemistry Frontiers 4, p.1615–1619 |
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摘要 | A highly chemo- and stereoselective nickel-catalyzed borylative cyclization of 1,6-enynes with bis(pinacolato)diboron is described. Enynes containing an electron-deficient alkene such as a vinyl ketone provided alkenylboronates while enynes containing a terminal alkene gave homoallylic boronates. A plausible mechanism involving a nickelacyclopentene intermediate is proposed. In addition, the resulted alkenyl- or homoallylic boronates can be transformed to the corresponding ketones and alcohols via oxidation. Application to a palladium-catalyzed cross coupling reaction of alkenylboronates with aromatic halides has been demonstrated as well. |
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關鍵字 | |
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語言 | 英文 |
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ISSN | |
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期刊性質 | 國外 |
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收錄於 | SCI; |
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產學合作 | |
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通訊作者 | |
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審稿制度 | 是 |
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國別 | 英國 |
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公開徵稿 | |
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出版型式 | ,電子版,紙本 |
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相關連結 | |
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