| Reinvestigation of synthesis of halo-substituted 3-phenyl-1-(2-pyridyl)-2-propen-1-ones (azachalcones). A tandem reaction for formation of penta-substituted cyclohexanols | |
|---|---|
| 學年 | 106 |
| 學期 | 1 |
| 出版（發表）日期 | 2017-08-03 |
| 作品名稱 | Reinvestigation of synthesis of halo-substituted 3-phenyl-1-(2-pyridyl)-2-propen-1-ones (azachalcones). A tandem reaction for formation of penta-substituted cyclohexanols |
| 作品名稱（其他語言） | |
| 著者 | Li, Chia-Wai; Shen, Tzu-Hsuan; Shih, Tzenge-Lien |
| 單位 | |
| 出版者 | |
| 著錄名稱、卷期、頁數 | Tetrahedron 73(31), p.4644–4652 |
| 摘要 | A systematic study of the synthesis of halo-substituted azachalcones was conducted. During the reaction course, we obtained not only the target azachalcones, but also penta-substituted cyclohexanols, which are seldom reported in the literatures. The formation of penta-substituted cyclohexanols was dependent on equivalents of base used and reaction time. Their formation followed a tandem reaction: Claisen-Schmidt condensation, three Michael reactions, retro-aldol reaction, and intramolecular aldol cyclization. |
| 關鍵字 | Azachalcone;Chalcone;Claisen-Schmidt condensation;Michael reactionxretro-aldol reaction;Tandem reaction |
| 語言 | en |
| ISSN | 0040-4020 |
| 期刊性質 | 國外 |
| 收錄於 | SCI |
| 產學合作 | |
| 通訊作者 | Shih, Tzenge-Lien |
| 審稿制度 | 是 |
| 國別 | GBR |
| 公開徵稿 | |
| 出版型式 | ,紙本 |
| 相關連結 |
機構典藏連結 ( http://tkuir.lib.tku.edu.tw:8080/dspace/handle/987654321/110526 ) |
| SDGS | 良好健康和福祉,優質教育 |
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