教師資料查詢 | 類別: 期刊論文 | 教師: 施增廉 SHIH, TZENGE-LIEN (瀏覽個人網頁)

標題:Synthesis of novel C4-benzazole naphthalimide derivatives with potent anti-tumor properties against murine melanoma
學年105
學期1
出版(發表)日期2017/01/15
作品名稱Synthesis of novel C4-benzazole naphthalimide derivatives with potent anti-tumor properties against murine melanoma
作品名稱(其他語言)
著者Yen-Ta Lu; Tien-Ling Chen; Kuo-Song Chang; Chia-Ming Chang; Tsai-Yin Wei; Jen-Wei Liu; Chih-Ang Hsiao; Tzenge-Lien Shih
單位
出版者
著錄名稱、卷期、頁數Bioorganic Medicinal Chemistry 25(2), p.789-794
摘要Novel C4-benzazole naphthalimide derivatives were synthesized and tested in vitro and in vivo as anti-cancer drugs. Among these synthetic molecules, compounds 9 and 10 exhibited cytotoxicity against murine B16F10 melanoma cells. In addition, the above-mentioned compounds significantly suppressed lung tumor metastasis with no visible sign of toxicity.
關鍵字Benzazole;B16F10 cells;Melanoma;MTS assay;Naphthalimide;Topoisomerase II
語言英文
ISSN0968-0896
期刊性質國外
收錄於SCI;
產學合作
通訊作者Tzenge-Lien Shih
審稿制度
國別英國
公開徵稿
出版型式,電子版,紙本
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