教師資料查詢 | 類別: 會議論文 | 教師: 鄭廖平 CHENG, LIAO-PING (瀏覽個人網頁)

標題:Preparation of asymmetric polyhydroxybutyrate/chitosan composite membrane for guided bone regeneration
學年102
學期1
發表日期2013/11/17
作品名稱Preparation of asymmetric polyhydroxybutyrate/chitosan composite membrane for guided bone regeneration
作品名稱(其他語言)
著者Trong-Ming Don; Hung-Yin Tai; Liao-Ping Cheng; Wei Lien
作品所屬單位
出版者
會議名稱The 13th Pacific Polymer Conference(PPC 2013)
會議地點Kaohsiung, Taiwan
摘要In this study, an asymmetric composite membrane composed of a porous chitosan layer and a dense polyhydroxybutyrate (PHB) layer was prepared, and its mechanical properties as well as cellular compatibility were evaluated. First, the PHB dense layer with a thickness of ca. 32 m was obtained by direct oven-drying. After being treated with plasma to produce free radicals on the surface and subsequently graft polymerized with poly(acrylic acid), the PHB was immersed in the CS solution where the CS chains could be chemically bonded to the PHB surface via carbodiimide activation. After lyophilization, an asymmetric PHB/CS composite membrane was obtained. Compared to the porous CS membrane, the composite membrane had higher tensile mechanical properties. In addition, the fibroblast cells (L929 and HGF) and human osteoblast cells (hFOB1.19) were cultured on both sides of the composite membrane. All the cells could proliferate very well indicating that both PHB and CS layers were cellular compatible. Yet, the PHB dense layer could prohibit the fibroblast cells to penetrate through the membrane. Thus, the asymmetric composite membrane can be use as a potential barrier membrane for guided bone regeneration in periodontal tissue engineering.
關鍵字
語言英文(美國)
收錄於
會議性質國內
校內研討會地點
研討會時間20131117~20131117
通訊作者Trong-Ming Don
國別中華民國
公開徵稿
出版型式
出處The 13th Pacific Polymer Conference Program book, Poster-S8-034, pp.107
相關連結
Google+ 推薦功能,讓全世界都能看到您的推薦!