教師資料查詢 | 類別: 期刊論文 | 教師: 楊龍杰 Yang Lung-jieh (瀏覽個人網頁)

標題:The Micro Patterning of Glutaraldehyde (GA)-Crosslinked Gelatin And Its Application To Cell-Culture
學年94
學期1
出版(發表)日期2005/08/01
作品名稱The Micro Patterning of Glutaraldehyde (GA)-Crosslinked Gelatin And Its Application To Cell-Culture
作品名稱(其他語言)
著者Yang, Lung-jieh; Ou, Yu-cheng
單位淡江大學機械與機電工程學系
出版者Cambridge: RSC Publications
著錄名稱、卷期、頁數Lab on a Chip 5(9), pp.979-984
摘要This paper proposes a novel technique for fabricating micro patterns of glutaraldehyde (GA)-crosslinked gelatin. It provides another means to crosslink gelatin other than using photo-sensitizing agents, and the micro patterns of GA-crosslinked gelatin can still be made successfully by accessing conventional photolithography. A much less toxic and increased biocompatible approach to strengthening the gelatin microstructures can be developed according to this idea. This paper also describes a potential methodology for using GA-crosslinked gelatin patterns as single-cell culture bases. The best spatial resolution of the micro gelatin bases can reach 10 µm, and the selective growing density of human Mesenchymal stem cells on the gelatin patterns surpasses the density on the glass substrate by 2–3 orders of magnitude.
關鍵字collagen; gelatin; glutaraldehyde; photosensitizing agent; protein; biocompatibility; biotechnology; cell adhesion; cell culture; cell density; cell growth; chemical structure; conference paper; controlled study; cross linking; culture medium; human; human cell; hydrophilicity; mesenchyme; particle size; photolithography; priority journal; robotics; stem cell; surface property; technique; Biocompatible Materials; Cell Culture Techniques; Cross-Linking Reagents; Gelatin; Glass; Glutaral; Humans; Mesenchymal Stem Cells; Nanotechnology
語言英文
ISSN1473-0189
期刊性質國際
收錄於SCI
產學合作
通訊作者Yang, Lung-Jieh
審稿制度
國別英國
公開徵稿
出版型式電子版
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