Dynamic Attachment of HepG2 in Fractal Microchannels | |
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學年 | 102 |
學期 | 2 |
發表日期 | 2014-04-16 |
作品名稱 | Dynamic Attachment of HepG2 in Fractal Microchannels |
作品名稱(其他語言) | |
著者 | Yang, Lung-Jieh; Liang, Jia-Chi; Liu, Cheng-Yang; Han, Hsieh-Cheng; |
作品所屬單位 | 淡江大學機械與機電工程學系 |
出版者 | |
會議名稱 | The 9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems |
會議地點 | Hawaii, USA |
摘要 | Dynamic filling experiments using HepG2 tumor cells are performed for observing the attachment behavior novelly in fractal microchannels. A PDMS microchannel mimicking the capillary blood vessel with fractal configuration is fabricated by the gelatin salt-out technique and the PDMS soft lithography. The fabrication of this low-toxicity fractal PDMS microchannel is firstly addressed herein. Using this PDMS microchannel, PBS with living HepG2 tumor cells are filled through. The cell attachment areas in the PDMS microchannel have been recorded dynamically with 10 min interval continuously for 2 hours. The result show that 2 hour is not enough for the permanent cell attachment of HepG2 in this fractal PDMS microchannel. |
關鍵字 | HepG2; blood vessels; fractal; PDMS |
語言 | en |
收錄於 | |
會議性質 | 國際 |
校內研討會地點 | |
研討會時間 | 20140416~20140416 |
通訊作者 | Yang, Lung-Jieh |
國別 | USA |
公開徵稿 | Y |
出版型式 | 紙本 |
出處 | The 9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, pp.51-54 |
相關連結 |
機構典藏連結 ( http://tkuir.lib.tku.edu.tw:8080/dspace/handle/987654321/98909 ) |