Dynamic Attachment of HepG2 in Fractal Microchannels
學年 102
學期 2
發表日期 2014-04-16
作品名稱 Dynamic Attachment of HepG2 in Fractal Microchannels
作品名稱（其他語言）
著者 Yang, Lung-Jieh; Liang, Jia-Chi; Liu, Cheng-Yang; Han, Hsieh-Cheng;
作品所屬單位 淡江大學機械與機電工程學系
出版者
會議名稱 The 9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems
會議地點 Hawaii, USA
摘要 Dynamic filling experiments using HepG2 tumor cells are performed for observing the attachment behavior novelly in fractal microchannels. A PDMS microchannel mimicking the capillary blood vessel with fractal configuration is fabricated by the gelatin salt-out technique and the PDMS soft lithography. The fabrication of this low-toxicity fractal PDMS microchannel is firstly addressed herein. Using this PDMS microchannel, PBS with living HepG2 tumor cells are filled through. The cell attachment areas in the PDMS microchannel have been recorded dynamically with 10 min interval continuously for 2 hours. The result show that 2 hour is not enough for the permanent cell attachment of HepG2 in this fractal PDMS microchannel.
關鍵字 HepG2; blood vessels; fractal; PDMS
語言 en
收錄於
會議性質 國際
校內研討會地點
研討會時間 20140416~20140416
通訊作者 Yang, Lung-Jieh
國別 USA
公開徵稿 Y
出版型式 紙本
出處 The 9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, pp.51-54
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