教師資料查詢 | 類別: 會議論文 | 教師: 陳以錚 YI-CHENG CHEN (瀏覽個人網頁)

標題:Cluster-based Classification of Diabetic Nephropathy among Type 2
學年102
學期2
發表日期2014/05/07
作品名稱Cluster-based Classification of Diabetic Nephropathy among Type 2
作品名稱(其他語言)
著者Guan-Mau Huang; Yu-Chun Lee; Julia Tzu-Ya Weng; Yi-Cheng Chen; Lawrence Shih-Hsin Wu
作品所屬單位資訊工程學系暨研究所
出版者
會議名稱The 3rd International Congress on Natural Sciences and Engineering (ICNSE'14)
會議地點Kyoto, Japan
摘要The prevalence of type 2 diabetes is increasing at an alarming rate. Various complications are associated with type 2 diabetes, with diabetic nephropathy being the leading cause of renal failure among diabetics. Often, when patients are diagnosed with diabetic nephropathy, their
renal functions have already been significantly damaged, speeding up the progression towards end stage renal disease. Therefore, a risk prediction tool may be beneficial for the implementation of early treatment and prevention. In the present study, we propose to develop a prediction model integrating clustering and classification approaches for the
identification of diabetic nephropathy among type 2 diabetes patients. Clinical and
genotyping data are obtained from 345 type 2 diabetic patients(160 with non-diabetic
nephropathy and 185 with diabetic nephropathy). The performance of using clinical features alone for cluster-based classification is compared with that of utilizing a combination of clinical and genetic attributes. We find that the inclusion of genetic features yield better
prediction results. Further refinement of the proposed approach has the potential to facilitate the accurate identification of diabetic nephropathy and the development of better treatment in a clinical setting.
關鍵字type 2 diabetes;diabetic nephropathy;classification;clustering;genetic
語言英文(美國)
收錄於EI
會議性質國際
校內研討會地點
研討會時間20140507~2014009
通訊作者Julia Tzu-Ya Weng
國別日本
公開徵稿Y
出版型式電子版
出處The 3rd International Congress on Natural Sciences and Engineering (ICNSE'14), pp. 861-867.
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