教師資料查詢 | 類別: 期刊論文 | 教師: 盧博堅 LU PO-CHIEN (瀏覽個人網頁)

標題:The effect of turbulent viscous shear stress on red blood cell hemolysis
學年102
學期2
出版(發表)日期2014/03/01
作品名稱The effect of turbulent viscous shear stress on red blood cell hemolysis
作品名稱(其他語言)
著者Yen, Jen-Hong; Chen, Sheng-Fu; Chern, Ming-Kai; Lu, Po-Chien
單位淡江大學水資源及環境工程學系
出版者Tokyo: Springer Japan KK
著錄名稱、卷期、頁數Journal of Artificial Organs 17(2), pp.178-185
摘要Non-physiologic turbulent flow occurs in medical cardiovascular devices resulting in hemodynamic stresses that may damage red blood cells (RBC) and cause hemolysis. Hemolysis was previously thought to result from Reynolds shear stress (RSS) in turbulent flows. A more recent hypothesis suggests that turbulent viscous shear stresses (TVSS) at spatial scales similar in size to RBCs are related to their damage. We applied two-dimensional digital particle image velocimetry to measure the flow field of a free-submerged axisymmetric jet that was utilized to hemolyze porcine RBCs in selected locations. Assuming a dynamic equilibrium for the sub-grid scale (SGS) energy flux between the resolved and the sub-grid scales, the SGS energy flux was calculated from the strain rate tensor computed from the resolved velocity fields. The SGS stress was determined by the Smagorinsky model, from which the turbulence dissipation rate and then TVSS were estimated. Our results showed the hemolytic threshold of the Reynolds stresses was up to 517 Pa, and the TVSSs were at least an order of magnitude less than the RSS. The results provide further insight into the relationship between turbulence and RBC damage.
關鍵字Hemolysis; Sub-grid scale; Turbulent dissipation rate; Viscous dissipative stresses; Particle image velocimetry
語言英文
ISSN1434-7229
期刊性質國外
收錄於SCI
產學合作
通訊作者Lu, Po-Chien
審稿制度
國別日本
公開徵稿
出版型式紙本
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