教師資料查詢 | 類別: 期刊論文 | 教師: 潘伯申 PO-SHEN PAN (瀏覽個人網頁)

標題:Synthesis of Boron-Containing Primary Amines
學年102
學期1
出版(發表)日期2013/10/01
作品名稱Synthesis of Boron-Containing Primary Amines
作品名稱(其他語言)
著者Chung, Sheng-Hsuan; Lin, Ting-Ju; Hu, Qian-Yu; Tsai, Chia-Hua; Pan, Po-Shen
單位淡江大學化學學系
出版者Basel: M D P I AG
著錄名稱、卷期、頁數Molecules 18(10), pp.12346-12367
摘要In this study, boron-containing primary amines were synthesized for use as building blocks in the study of peptoids. In the first step, Gabriel synthesis conditions were modified to enable the construction of seven different aminomethylphenyl boronate esters in good to excellent yields. These compounds were further utilized to build peptoid analogs via an Ugi four-component reaction (Ugi-4CR) under microwave irradiation. The prepared Ugi-4CR boronate esters were then successfully converted to the corresponding boronic acids. Finally, the peptoid structures were successfully modified by cross-coupling to aryl/heteroaryl chlorides via a palladium-mediated Suzuki coupling reaction to yield the corresponding derivatives in moderate to good yields.
關鍵字
語言英文
ISSN1431-5165;1420-3049
期刊性質國外
收錄於SCI;
產學合作
通訊作者Pan, Po-Shen
審稿制度
國別瑞士
公開徵稿
出版型式紙本
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