教師資料查詢 | 類別: 期刊論文 | 教師: 張玉坤 Yue-cune Chang (瀏覽個人網頁)

標題:The Impact of Arteriovenous Malformation Radiosurgery on the Brain: From Morphology and Perfusion to Neurocognition
學年95
學期1
出版(發表)日期2006/09/01
作品名稱The Impact of Arteriovenous Malformation Radiosurgery on the Brain: From Morphology and Perfusion to Neurocognition
作品名稱(其他語言)
著者Guo, W. Y.; Lee, S. M.; Chang, Y. C.; Pan, H. C.
單位淡江大學數學學系
出版者Basel: S. Karger AG
著錄名稱、卷期、頁數Stereotactic and Functional Neurosurgery 84(4), pp.162-169
摘要The therapeutic aims of brain arteriovenous malformation (AVM) radiosurgery are multiple. Protecting patients from rebleeding is the prime goal. Among the others, hemodynamics, perfusion and neurocognition recovery are interesting and important. Anatomically AVM contains an abnormal cluster of vascular networks (nidus) between arteries and veins. Hemodynamically the nidus contains a low resistance and causes high-flow transnidal shunts between both sides of the nidus. The shunts cause hypotension in the neighboring arteries and diversion of blood from the adjacent brain tissues. The diversion disturbs brain hemodynamics. Radiosurgery, by eliminating the nidus, reconstitutes normal brain hemodynamics. From the early stage after radiosurgery, the abnormal transnidal flows gradually decrease, and the adjacent hemodynamics recovers toward normal. For nonhemorrhagic AVM, improvement of seizure control and stable or improved neurological status are observed clinically. The radiosurgical effects are also reflected in the recovery of metabolism in the adjacent brain and neurocognitive function paralleling the hemodynamic normalization. Morphological cure of AVM and the associated recovery of brain hemodynamics, metabolism and neurocognitive function form the therapeutic rationale of AVM radiosurgery.
關鍵字adolescent;adult;arteriovenous malformation;arteriovenous shunt;brain hemorrhage;brain perfusion;brain surgery;clinical article;cognition;conference paper;controlled study;female;human;hypotension;male;radiosurgery;Adolescent;Adult;Cerebral Angiography;Cerebrovascular Circulation;Cognition Disorders;Female;Humans;Intracranial Arteriovenous Malformations;Magnetic Resonance Angiography;Male;Postoperative Complications;Prospective Studies;Radiosurgery;Recovery of Function;Treatment Outcome
語言英文
ISSN1011-6125
期刊性質國外
收錄於
產學合作
通訊作者
審稿制度
國別史瓦濟蘭
公開徵稿
出版型式紙本
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