教師資料查詢 | 類別: 期刊論文 | 教師: 陳銘凱 CHERN MING-KAI (瀏覽個人網頁)

標題:Betaine aldehyde dehydrogenase from rat liver mitochondrial matrix
學年89
學期1
出版(發表)日期2001/01/01
作品名稱Betaine aldehyde dehydrogenase from rat liver mitochondrial matrix
作品名稱(其他語言)
著者Pietruszko, Regina; Chern, Ming-kai
單位淡江大學生命科學研究所
出版者Shannon: Elsevier Ireland Ltd
著錄名稱、卷期、頁數Chemico-Biological Interactions 130-132, pp.193-199
摘要An NAD-linked aldehyde dehydrogenase which in addition to aliphatic and aromatic aldehydes, metabolizes aminoaldehydes and betaine aldehyde, has been purified to homogeneity from male Sprague–Dawley rat liver mitochondria. The properties of the rat mitochondrial enzyme are similar to those of a rat liver cytoplasmic betaine aldehyde dehydrognase and the human cytoplasmic E3 isozyme. The primary structure. of four tryptic peptides were also similar; only one difference in primary structure was observed. The close similarity of properties of the cytoplasmic with the mitochondrial form suggest that the cytoplasmic and mitochondrial betaine aldehyde dehydrogenase may be coded for by the same nuclear gene. Investigation of the mitochondrial form by isoelectric focusing resulted in visualization of multiple forms, different from those seen in the cytoplasm suggesting that the enzyme may be processed in the mitochondria.
關鍵字Betaine aldehyde dehydrogenase;Mitochondria;Rat liver;Localization
語言英文
ISSN0009-2797
期刊性質國外
收錄於
產學合作
通訊作者Pietruszko, Regina
審稿制度
國別愛爾蘭
公開徵稿
出版型式紙本
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